Anti-STEA3 STEAP3 Antibody

Product Name

Anti-STEA3 STEAP3 Antibody

View all STEAP3/TSAP6 Antibodies

SKU/Catalog Number

A05568

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-STEA3 STEAP3 Antibody (Catalog # A05568). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-STEA3 STEAP3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05568)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human STEA3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05568 is reactive to STEAP3 in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

111 kDa

Calculated molecular weight

54601 MW

Background of STEAP3/TSAP6

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003).
Korkmaz C.G., Oncogene 24:4934-4945(2005).
Steiner M.S., Cancer Res. 60:4419-4425(2000).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A05568 is guaranteed for IF, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Validation Images & Assay Conditions

Gene/Protein Information For STEAP3 (Source: Uniprot.org, NCBI)

Alternative Names

Metalloreductase STEAP3;1.16.1.-;Dudulin-2;Six-transmembrane epithelial antigen of prostate 3;Tumor suppressor-activated pathway protein 6;hTSAP6;pHyde;hpHyde;STEAP3;TSAP6; STEAP3 AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde STEAP3 metalloreductase metalloreductase STEAP3|STEAP family member 3, metalloreductase|six-transmembrane epithelial of prostate 3|tumor suppressor pHyde|tumor suppressor-activated pathway protein 6

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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