Metalloreductase STEAP3 Antibodies

AND STEAP3 ELISA kits, Metalloreductase STEAP3 Proteins

Many biological assays use antibodies to detect Metalloreductase STEAP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Metalloreductase STEAP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Metalloreductase STEAP3 antibodies...

We validate the specificity of these antibodies to Metalloreductase STEAP3 by testing them on tissues known to express STEAP3 positively and negatively. Browse below to find the STEAP3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STEAP3 Infographic by Boster Bio

All STEAP3 Products

Product

Figures

Specificity

Applications

Price

Anti-STEA3 STEAP3 Antibody

4 Q&As

Human, Mouse, Rat

IF, WB

$360
Cat # A05568
100 µl

Anti-STEA3 Antibody

1 Q&As

Human, Mouse, Rat

ELISA, IF, IHC-P, ICC, WB

$335
Cat # A30509
100ul

STEA3 Colorimetric Cell-Based ELISA

Human, Mouse, Rat

ELISA

$480
Cat # EKC1854
1 kit, containing one 96-well plate and all necessary reagents

Anti-Metalloreductase STEAP3 STEAP3 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A05568-1
0.1 mg

STEAP3 (NM_001008410) Human Recombinant Protein

$1249
Cat # PROTQ658P3
20 µg

STEAP3 (NM_018234) Human Over-expression Lysate

Human

$628
Cat # LS055240
100 µg

STEAP3 Overview

Facts about Metalloreductase STEAP3.

STEAP3 3D structure. Source: alphafold

Metalloreductase STEAP3 (STEAP3)

Endosomal ferrireductase needed for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+).

Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor.

Gene Information

Human
Gene Name:	STEAP3
Uniprot:	Q658P3
Entrez:	55240

Family

Belongs to:

STEAP family

Alternative Names

AHMIO2; dudlin 2; Dudlin-2; dudulin 2; dudulin-2; Dudulin-2,1010001D01Rik; EC 1.16.1.-; hpHyde; hTSAP6; metalloreductase STEAP3; pHyde; six transmembrane prostate protein 3; Six-transmembrane epithelial antigen of prostate 3; STEAP family member 3; STEAP3; STMP3; TSAP6; TSAP6STMP3; tumor suppressor pHyde; Tumor suppressor-activated pathway protein 6

Molecular Weight

Mass (kDA):
54.601 kDA

Genomic Context


Human

Location:	2q14.2
Sequence:	2; NC_000002.12 (119222476..119265652)

Tissue Specificity

Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma.

Subcellular Localizations

Endosome membrane; Multi-pass membrane protein. Localizes to vesicular-like structures at the plasma membrane and around the nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Microcytic Anemia
Anemia
Sarcoma
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Carcinoma
Malignant Paraganglionic Neoplasm
Iron Deficiency Anemia
Obesity
Iron Deficiency
Disease Of Adrenal Medulla

Stenosis
Tumor Progression
Malignant Neoplasm Of Urinary Bladder
Malignant Neoplasm Of Lung
Immunologic Deficiency Syndromes
Pathologic Fistula
Microcytic Hypochromic Anemia (disorder)

Pathways

Secretion
Transport
Localization
Receptor-mediated Endocytosis
Secretory Pathway
Transmembrane Transport
Cell Proliferation
Catecholamine Secretion

Protein Secretion
Endocytosis
Pathogenesis

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STEAP3

References

PMID: 12606722 by Passer B.J., et al. The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase.

PMID: 15897894 by Korkmaz C.G., et al. Molecular cloning and characterization of STAMP2, an androgen- regulated six transmembrane protein that is overexpressed in prostate cancer.