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Product Info Summary
| SKU: | PB9229 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Kv4.3/KCND3 Antibody Picoband®
SKU/Catalog Number
PB9229
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Kv4.3/KCND3 Antibody Picoband® catalog # PB9229. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Kv4.3/KCND3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9229)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
E.coli-derived human Kv4.3 recombinant protein (Position: M1-H177). Human Kv4.3 shares 100% and 99% amino acid (aa) sequences identity with mouse and rat Kv4.3, respectively.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PB9229 is reactive to KCND3 in Human, Mouse
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
73 kDa
Calculated molecular weight
73451 MW
Background of Kv4.3
Potassium voltage-gated channel subfamily D member 3, also known as Kv4.3, is a protein that in humans is encoded by the KCND3 gene. KCND3 is a member of the potassium channel, voltage-gated, shal-related subfamily. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. It is mapped to 1p13.2. KCND3 is important in membrane repolarization in excitable cells. It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PB9229 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Mouse, Human
Positive Control
WB: Mouse Brain Tissue
Validation Images & Assay Conditions
Click image to see more details
Anti-Kv4.3 antibody, PB9229, Western blotting
All lanes: Anti Kv4.3 (PB9229) at 0.5ug/ml
WB: Mouse Brain Tissue Lysate at 50ug
Predicted bind size: 73KD
Observed bind size: 73KD
Protein Target Info & Infographic
Gene/Protein Information For KCND3 (Source: Uniprot.org, NCBI)
Gene Name
KCND3
Full Name
Potassium voltage-gated channel subfamily D member 3
Weight
73451 MW
Superfamily
potassium channel family
Alternative Names
Potassium voltage-gated channel subfamily D member 3;Voltage-gated potassium channel subunit Kv4.3;KCND3; KCND3 BRGDA9L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22, KCND3 potassium voltage-gated channel subfamily D member 3 potassium voltage-gated channel subfamily D member 3|potassium channel, voltage gated Shal related subfamily D, member 3|potassium ionic channel Kv4.3|potassium voltage-gated channel long|potassium voltage-gated channel, Shal-related subfamily, member 3|sha1-related potassium channel Kv4.3|voltage-gated K+ channel|voltage-gated potassium channel subunit Kv4.3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCND3, check out the KCND3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCND3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Kv4.3/KCND3 Antibody Picoband® (PB9229)
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No publications found for PB9229
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Customer Q&As
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4 Customer Q&As for Anti-Kv4.3/KCND3 Antibody Picoband®
Question
See below the WB image, lot number and protocol we used for brain heart using anti-Kv4.3/KCND3 antibody PB9229. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2019-12-27
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-12-27
Question
We are currently using anti-Kv4.3/KCND3 antibody PB9229 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse. Is it true that the antibody can work on feline tissues as well?
Verified Customer
Verified customer
Asked: 2019-11-18
Answer
The anti-Kv4.3/KCND3 antibody (PB9229) has not been tested for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-11-18
Question
I was wanting to use your anti-Kv4.3/KCND3 antibody for WB for human brain heart on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human brain heart identification?
S. Dhar
Verified customer
Asked: 2018-01-16
Answer
You can see on the product datasheet, PB9229 anti-Kv4.3/KCND3 antibody has been validated for WB on human, mouse tissues. We have an innovator award program that if you test this antibody and show it works in human brain heart in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2018-01-16
Question
Is a blocking peptide available for product anti-Kv4.3/KCND3 antibody (PB9229)?
M. Wu
Verified customer
Asked: 2016-07-20
Answer
We do provide the blocking peptide for product anti-Kv4.3/KCND3 antibody (PB9229). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2016-07-20
