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Product Info Summary
| SKU: | A04502-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-KCNK1 Antibody
SKU/Catalog Number
A04502-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KCNK1 Antibody (Catalog # A04502-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
KCNK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-KCNK1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04502-1)
Host
Rabbit
Contents
KCNK1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KCNK1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1. The immunogen is located within amino acids 220 - 270 of KCNK1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
KCNK1 antibody is human, mouse and rat reactive. KCNK1 antibody is predicted to not cross-react with other KCNK proteins.
Reactive Species
A04502-1 is reactive to KCNK1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
38143 MW
Background of KCNK1
The potassium channel, subfamily K, member 1 (KCNK1), is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1,2). KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1). Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04502-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KCNK1 antibody can be used for detection of KCNK1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KCNK1 in 3T3 cell lysate with KCNK1 antibody at 1 μg/ml.
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Immunohistochemistry of KCNK1 in mouse brain tissue with KCNK1 antibody at 5 μg/ml.
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Immunofluorescence of KCNK1 in mouse brain tissue with KCNK1 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For KCNK1 (Source: Uniprot.org, NCBI)
Gene Name
KCNK1
Full Name
Potassium channel subfamily K member 1
Weight
38143 MW
Superfamily
two pore domain potassium channel (TC 1.A.1.8) family
Alternative Names
Potassium channel subfamily K member 1, DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1 KCNK1 DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1 potassium two pore domain channel subfamily K member 1 potassium channel subfamily K member 1|inward rectifying potassium channel protein TWIK-1|potassium channel K2P1|potassium channel KCNO1|potassium channel, two pore domain subfamily K, member 1|potassium inwardly-rectifying channel, subfamily K, member 1|tandem of P domains in a weak inward rectifying K+ channel 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNK1, check out the KCNK1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNK1 Antibody (A04502-1)
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