Anti-KANK1 Antibody

ANKRD15 antibody

Boster Bio Anti-KANK1 Antibody (Catalog # M05029). Tested in WB, IHC-P application(s). This antibody reacts with Human.

Product Info Summary

SKU: M05029
Size: 50 µl
Reactive Species: Human
Host: Mouse
Application: IHC-P, WB

Product Name

Anti-KANK1 Antibody

View all ANKRD15 Antibodies

SKU/Catalog Number

M05029

Size

50 µl

Description

Boster Bio Anti-KANK1 Antibody (Catalog # M05029). Tested in WB, IHC-P application(s). This antibody reacts with Human.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-KANK1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M05029)

Host

Mouse

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Monoclonal

Clone Number

1773CT634.49.61

Isotype

IgG1,k

Immunogen

This KANK1 antibody is generated from a mouse immunized with a recombinant protein of human KANK1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M05029 is reactive to KANK1 in Human

Reconstitution

Calculated molecular weight

147289 Da

Background of ANKRD15

Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M05029 is guaranteed for IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:2000
IHC-P: 1:25

Validation Images & Assay Conditions

Gene/Protein Information For KANK1 (Source: Uniprot.org, NCBI)

Gene Name

KANK1

Full Name

KN motif and ankyrin repeat domain-containing protein 1

Weight

147289 Da

Alternative Names

KN motif and ankyrin repeat domain-containing protein 1, Ankyrin repeat domain-containing protein 15, Kidney ankyrin repeat-containing protein, KANK1, ANKRD15, KANK, KIAA0172 KANK1 ANKRD15, CPSQ2, KANK KN motif and ankyrin repeat domains 1 KN motif and ankyrin repeat domain-containing protein 1|ankyrin repeat domain-containing protein 15|kidney ankyrin repeat-containing protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on KANK1, check out the KANK1 Infographic

KANK1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for KANK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M05029-50ul

50 μl

$299
M05029-200ul

200 μl

$347

Free Secondary Antibody

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M05029
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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