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Product Info Summary
| SKU: | A05029 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-KANK1 Antibody
SKU/Catalog Number
A05029
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KANK1 Antibody (Catalog # A05029). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
KANK1 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-KANK1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05029)
Host
Rabbit
Contents
KANK1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1 . The immunogen is located within the first 50 amino acids of KANK1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Two alternatively spliced transcript variants encoding different isoforms have been identified. The lower molecular weight band seen in the immunoblot is thought to be non-specific.
Reactive Species
A05029 is reactive to KANK1 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
147289 MW
Background of ANKRD15
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05029 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KANK1 Antibody can be used for detection of KANK1 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KANK1 in 3T3 cell lysate with KANK1 antibody at 1 μg/mL.
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Immunohistochemistry of KANK1 in human kidney tissue with KANK1 antibody at 2.5 μg/ml.
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Immunofluorescence of KANK1 in human kidney tissue with KANK1 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For KANK1 (Source: Uniprot.org, NCBI)
Gene Name
KANK1
Full Name
KN motif and ankyrin repeat domain-containing protein 1
Weight
147289 MW
Alternative Names
KANK, CPSQ2, ANKRD15, KANK, KIAA0172, KN motif and ankyrin repeat domain-containing protein 1, Ankyrin repeat domain-containing protein 15 KANK1 ANKRD15, CPSQ2, KANK KN motif and ankyrin repeat domains 1 KN motif and ankyrin repeat domain-containing protein 1|ankyrin repeat domain-containing protein 15|kidney ankyrin repeat-containing protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KANK1, check out the KANK1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KANK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KANK1 Antibody (A05029)
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