KANK1 Antibodies

AND KANK1 ELISA kits, KANK1 Proteins

Many biological assays use antibodies to detect KANK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KANK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KANK1 antibodies...

We validate the specificity of these antibodies to KANK1 by testing them on tissues known to express KANK1 positively and negatively. Browse below to find the KANK1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KANK1 Infographic by Boster Bio

All KANK1 Products

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Product

Figures

Specificity

Applications

Price

Anti-KANK1 Antibody

Human, Mouse

ELISA, IF, IHC-P, WB

$449
Cat # A05029
0.1 mg

Anti-KANK1 Antibody

Human

IHC-P, WB

$299
Cat # M05029
50 µl

ANKRD15 (KANK1) (NM_015158) Human Over-expression Lysate

Human

$628
Cat # LS023189
100 µg

KANK1 Overview

Facts about KN motif and ankyrin repeat domain-containing protein 1.

KANK1 3D structure. Source: alphafold

KN motif and ankyrin repeat domain-containing protein 1 (KANK1)

Inhibits actin fiber formation and cell migration (PubMed:25961457). Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and might be based on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes (PubMed:25961457).

Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1 (PubMed:25961457). Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2.

Gene Information

Human
Gene Name:	KANK1
Uniprot:	Q14678
Entrez:	23189

Family

Belongs to:

No superfamily

Alternative Names

ANKRD15ankyrin repeat domain 15; Ankyrin repeat domain-containing protein 15; KANKDKFZp451G231; KIAA0172MGC43128; Kidney ankyrin repeat-containing protein; KN motif and ankyrin repeat domain-containing protein 1; KN motif and ankyrin repeat domains 1

Molecular Weight

Mass (kDA):
147.289 kDA

Genomic Context


Human

Location:	9p24.3
Sequence:	9; NC_000009.12 (470291..746106)

Tissue Specificity

Widely expressed. Isoform 1 is predominantly expressed in heart and kidney. Isoform 2 probably is widely expressed at basic levels.

Subcellular Localizations

Cell projection, ruffle membrane. Cytoplasm. Nucleus. Colocalizes with KIF21A in membrane ruffles (PubMed:19559006). Shuttles between the cytoplasm and nucleus (PubMed:16968744).; [Isoform 1]: Cytoplasm. Nucleus. Shuttles between the cytoplasm and nucleus.; [Isoform 2]: Cytoplasm. Nucleus. Shuttles between the cytoplasm and nucleus.