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Product Info Summary
| SKU: | A00455 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-IL8 beta CXCR2 Antibody
View all CXCR2/IL-8RB Antibodies
SKU/Catalog Number
A00455
Size
100ul
Form
Liquid
Description
Boster Bio Anti-IL8 beta CXCR2 Antibody catalog # A00455. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IL8 beta CXCR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00455)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human IL-8Rbeta.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00455 is reactive to CXCR2 in Human
Applications
A00455 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
40759 MW
Background of CXCR2/IL-8RB
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
Validation Images & Assay Conditions
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Figure 2. Immunohistochemistry validation of CXCR2 using Anti-IL8 beta CXCR2 Antibody (A00455).
Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain
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Figure 3. Immunohistochemistry validation of CXCR2 using Anti-IL8 beta CXCR2 Antibody (A00455).
Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain
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Figure 1. Western blotting validation for Anti-IL8 beta CXCR2 Antibody A00455
Western Blot (WB) analysis of HuvEc cells using IL-8Rbeta polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CXCR2 (Source: Uniprot.org, NCBI)
Gene Name
CXCR2
Full Name
C-X-C chemokine receptor type 2
Weight
40759 MW
Superfamily
G-protein coupled receptor 1 family
Alternative Names
CD182 antigen; CD182; CDw128b; chemokine (C-X-C motif) receptor 2; chemokine (CXC) receptor 2; CMKAR2; C-X-C chemokine receptor type 2; CXCR2 gene for IL8 receptor type B; CXCR2; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8 RB; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; IL8RB; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin-8 receptor type B CXCR2 CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB C-X-C motif chemokine receptor 2 C-X-C chemokine receptor type 2|CXC-R2|CXCR-2|CXCR2 gene for IL8 receptor type B|GRO/MGSA receptor|IL-8 receptor type 2|IL-8R B|chemokine (CXC) receptor 2|high affinity interleukin-8 receptor B|interleukin 8 receptor type 2|interleukin 8 receptor, beta|interleukin-8 receptor type B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CXCR2, check out the CXCR2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CXCR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL8 beta CXCR2 Antibody (A00455)
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No publications found for A00455
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