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Product Info Summary
| SKU: | A09203 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-IL-1RL2 Antibody
View all IL-1Rrp2/IL-1R6 Antibodies
SKU/Catalog Number
A09203
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IL-1RL2 Antibody (Catalog # A09203). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
IL-1RL2 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-IL-1RL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09203)
Host
Rabbit
Contents
IL-1RL2 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
IL-1RL2 antibody was raised against a 16 amino acid peptide near the center of human IL-1RL2. The immunogen is located within amino acids 260 - 310 of IL-1RL2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist; this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1.
Reactive Species
A09203 is reactive to IL1RL2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
65405 MW
Background of IL-1Rrp2/IL-1R6
IL-1RL2 is a member of the interleukin 1 receptor family, but it is incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity (1). Together with IL-1RAcP, it can bind members of the IL-36 cytokine family, leading to activation of the NF-kappaB pathway (2). IL-1RL2 can also bind to IL-1F10, resulting in a decreased product of Th17 cytokines in response to immunological or LPS challenge, suggesting that one potential role of IL-1RL2 may be to modulate the immune and inflammation response (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09203 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IL-1RL2 antibody can be used for detection of IL-1RL2 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IL-1RL2 in human small intestine lysate with IL-1RL2 antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of IL-1RL2 in human small intestine tissue with IL-1RL2 antibody at 5 μg/mL.
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Immunofluorescence of IL-1RL2 in human small intestine tissue with IL-1RL2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For IL1RL2 (Source: Uniprot.org, NCBI)
Gene Name
IL1RL2
Full Name
Interleukin-1 receptor-like 2
Weight
65405 MW
Superfamily
interleukin-1 receptor family
Alternative Names
IL-36R, IL1RRP2, IL-1Rrp2, IL1R-rp2, Interleukin-1 receptor-like 2, IL-36 receptor, IL-36R IL1RL2 IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2 interleukin 1 receptor like 2 interleukin-1 receptor-like 2|IL-1 receptor-related protein 2|IL-36 receptor|interleukin-1 receptor-related protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL1RL2, check out the IL1RL2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL1RL2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL-1RL2 Antibody (A09203)
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