Anti-Human SCRIBBLE DyLight® 550 conjugated Antibody

Product Name

Anti-Human SCRIBBLE DyLight® 550 conjugated Antibody

View all Scribble Antibodies

SKU/Catalog Number

A01651-Dyl550

Size

100 μg/vial

Form

Liquid

Description

Boster Bio Anti-Human SCRIBBLE DyLight® 550 conjugated Antibody catalog # A01651-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Cite This Product

Anti-Human SCRIBBLE DyLight® 550 conjugated Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01651-Dyl550)

Host

Rabbit

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human SCRIBBLE recombinant protein (Position: F172-K409).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01651-Dyl550 is reactive to SCRIB in Human

Applications

A01651-Dyl550 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

Background of Scribble

SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells

Validation Images & Assay Conditions

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Boster Kit Box

Gene/Protein Information For SCRIB (Source: Uniprot.org, NCBI)

Alternative Names

protein scribble homolog; CRIB1; SCRB1; SCRIB1; scribbled homolog (Drosophila); Vartul SCRIB CRIB1, SCRB11, Vartul, SCRIB scribble planar cell polarity protein protein scribble homolog|scribbled homolog|scribbled planar cell polarity protein

For more info on SCRIB, check out the SCRIB Infographic

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In this infographic, you will see the following information for SCRIB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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