Anti-Hu CD209 Purified Monoclonal Antibody

Product Name

Anti-Hu CD209 Purified Monoclonal Antibody

View all CD209 Antibodies

SKU/Catalog Number

M01025-2

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD209 Purified Monoclonal Antibody (Catalog# M01025-2). Tested in Flow Cytometry, IHC, ICC application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD209 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01025-2)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

UW60.1

Isotype

Mouse IgG2a

Immunogen

CD209-His-tagged fusion protein. The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01025-2 is reactive to CD209 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

45775 MW

Background of CD209

CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M01025-2 is guaranteed for Flow Cytometry, IHC, ICC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For CD209 (Source: Uniprot.org, NCBI)

Alternative Names

CLEC4L, DC-SIGN1, CDSIGN CD209 CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1 CD209 molecule CD209 |C-type lectin domain family 4 member L|HIV gpl20-binding protein|dendritic cell-specific ICAM-3-grabbing non-integrin 1|dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin|dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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