Recombinant Human IFN gamma Protein

Product Name

Recombinant Human IFN gamma Protein

View all IFN-gamma recombinant proteins

SKU/Catalog Number

R00393

Size

100μg/vial

Description

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulatedwith phytohemagglutinin, and by others as a productofantigen-stimulatedlymphocytes ortuberculin-sensitized mouseperitoneal lymphocytes challenged with PPD.The resulting supernatants were shown toinhibit growth of vesicular stomatitisvirus. IFNγis a cytokine that is critical for innate and adaptive immunityagainst viral, some bacterial and protozoal infections. IFNγ is an important activator of macrophages and inducer of Class II major histocompatibility complex (MHC) molecule expression. The importance of IFNγ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatoryand immunomodulatoryeffects. IFNγ is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.

Storage & Handling

Lyophilized recombinant human Interferon gamma remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIFNγremains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

Cite This Product

Recombinant Human IFN gamma Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # R00393)

Form

Lyophilized

Formulation

Reconstitute in ddH2O at 100 μg/mL.

Purity

>95%, by SDS-PAGE quantitative densitometry by Coomassie® Blue Staining.

Predicted MW

16.1KD

Endotoxin

Less than 1 EU/μg of IFNγ as determined by LAL method.

Validation Images & Assay Conditions

Gene/Protein Information For IFNG (Source: Uniprot.org, NCBI)

Alternative Names

IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma IFNG IFG, IFI, IMD69 interferon gamma interferon gamma|IFN-gamma|immune interferon

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

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