Anti-Hu CD102 Purified ICAM2 Monoclonal Antibody

Product Name

Anti-Hu CD102 Purified ICAM2 Monoclonal Antibody

View all ICAM-2/CD102 Antibodies

SKU/Catalog Number

M04901

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD102 Purified ICAM2 Monoclonal Antibody (Catalog# M04901). Tested in Flow Cytometry, IP, IHC-F application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD102 Purified ICAM2 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04901)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

CBR-IC2/2

Isotype

Mouse IgG2a

Immunogen

Human CD102 cDNA transfected COS cells. The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody does not cross-react with Thy-1.1 alloantigen.

Reactive Species

M04901 is reactive to ICAM2 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

30654 MW

Background of ICAM-2/CD102

CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M04901 is guaranteed for Flow Cytometry, IP, IHC-F Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 2-4 μg/ml.

Validation Images & Assay Conditions

Gene/Protein Information For ICAM2 (Source: Uniprot.org, NCBI)

Alternative Names

ICAM2 ICAM2 CD102 intercellular adhesion molecule 2 intercellular adhesion molecule 2|ICAM-2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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