Anti-hnRNP C1/C2 Antibody

Product Name

Anti-hnRNP C1/C2 Antibody

View all hnRNP C1 + C2 Antibodies

SKU/Catalog Number

A02726

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-hnRNP C1/C2 Antibody (Catalog # A02726). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-hnRNP C1/C2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02726)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human hnRNP C1/C2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02726 is reactive to HNRNPC in Human, Mouse, Rat

Reconstitution

Calculated molecular weight

33670 MW

Background of hnRNP C1 + C2

Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Burd C.G., Proc. Natl. Acad. Sci. U.S.A. 86:9788-9792(1989).
Swanson M.S., Mol. Cell. Biol. 7:1731-1739(1987).
Merrill B.M., Nucleic Acids Res. 17:8441-8449(1989).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A02726 is guaranteed for IF, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Validation Images & Assay Conditions

Gene/Protein Information For HNRNPC (Source: Uniprot.org, NCBI)

Alternative Names

Heterogeneous nuclear ribonucleoproteins C1/C2;hnRNP C1/C2;HNRNPC;HNRPC; HNRNPC C1, C2, HNRNP, HNRPC, SNRPC heterogeneous nuclear ribonucleoprotein C heterogeneous nuclear ribonucleoproteins C1/C2|heterogeneous nuclear ribonucleoprotein C (C1/C2)|hnRNP C1/C2|nuclear ribonucleoprotein particle C1 protein|nuclear ribonucleoprotein particle C2 protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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