Anti-hGH Purified GH1 Monoclonal Antibody

Product Name

Anti-hGH Purified GH1 Monoclonal Antibody

View all Growth Hormone Antibodies

SKU/Catalog Number

M00851-2

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-hGH Purified GH1 Monoclonal Antibody (Catalog# M00851-2). Tested in IHC-P, ICC, ELISA application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-hGH Purified GH1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00851-2)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

GH-45

Isotype

Mouse IgG1

Immunogen

Human growth hormone. The mouse monoclonal antibody GH-45 recognizes human growth hormone (hGH), a polypeptide hormone synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. The GH-45 antibody reacts with affinity constant 3.8 x 10¹⁰ l /mol; it does not bind human prolactin or any other pituitary hormones.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00851-2 is reactive to GH1 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

24847 MW

Background of Growth Hormone

CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00851-2 is guaranteed for ELISA, IHC-P, ICC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry: 5-10 μg/ml.

Validation Images & Assay Conditions

Gene/Protein Information For GH1 (Source: Uniprot.org, NCBI)

Alternative Names

Somatotropin, Growth hormone GH1 GH, GH-N, GHB5, GHN, IGHD1A, IGHD1B, IGHD2, hGH-N growth hormone 1 somatotropin|growth hormone B5|pituitary growth hormone

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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