Anti-HES7 HEXIM1 Antibody

Product Name

Anti-HES7 HEXIM1 Antibody

View all Hexim 1 Antibodies

SKU/Catalog Number

A02321-1

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-HES7 HEXIM1 Antibody (Catalog # A02321-1). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HES7 HEXIM1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02321-1)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from Internal of human HEXIM1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02321-1 is reactive to HEXIM1 in Human, Mouse, Rat

Reconstitution

Calculated molecular weight

40623 MW

Background of Hexim 1

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.

Kusuhara M., Biomed. Res. 20:273-279(1999).
Wittmann B.M., Cancer Res. 63:5151-5158(2003).
Ouchida R., Genes Cells 8:95-107(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A02321-1 is guaranteed for IF, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000 Immunohistochemistry: 1/100 - 1/300.

Immunofluorescence: 1:100~1:500

Validation Images & Assay Conditions

Gene/Protein Information For HEXIM1 (Source: Uniprot.org, NCBI)

Alternative Names

Protein HEXIM1;Cardiac lineage protein 1;Estrogen down-regulated gene 1 protein;Hexamethylene bis-acetamide-inducible protein 1;Menage a quatre protein 1;HEXIM1;CLP1, EDG1, HIS1, MAQ1; HEXIM1 CLP1, EDG1, HIS1, MAQ1 HEXIM P-TEFb complex subunit 1 protein HEXIM1|HMBA-inducible|cardiac lineage protein 1|estrogen down-regulated gene 1 protein|hexamethylene bis-acetamide inducible 1|hexamethylene bis-acetamide-inducible protein 1|hexamethylene bisacetamide inducible 1|hexamethylene bisacetamide-inducible protein|hexamethylene-bis-acetamide-inducible transcript 1|hexamthylene bis-acetamide inducible 1|menage a quatre 1|menage a quatre protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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