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Product Info Summary
| SKU: | A01647 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-GNE/Glcne Antibody
View all N-Acetylmannosamine Kinase/GNE Antibodies
SKU/Catalog Number
A01647
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-GNE/Glcne Antibody (Catalog # A01647). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GNE/Glcne Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01647)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human GNE.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01647 is reactive to GNE in Human, Mouse
Reconstitution
Calculated molecular weight
79275 MW
Background of N-Acetylmannosamine Kinase/GNE
Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.
Lucka L., FEBS Lett. 454:341-344(1999).
Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).
Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01647 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
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Western blot analysis of extracts from NIH/3T3 cells, using GNE antibody A01647.
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Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using GNE antibody A01647.
Protein Target Info & Infographic
Gene/Protein Information For GNE (Source: Uniprot.org, NCBI)
Gene Name
GNE
Full Name
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Weight
79275 MW
Alternative Names
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase;UDP-GlcNAc-2-epimerase/ManAc kinase;UDP-N-acetylglucosamine 2-epimerase (hydrolyzing);3.2.1.183;UDP-GlcNAc-2-epimerase;Uridine diphosphate-N-acetylglucosamine-2-epimerase;N-acetylmannosamine kinase;2.7.1.60;ManAc kinase;GNE;GLCNE; GNE DMRV, GLCNE, IBM2, NM, Uae1 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase|N-acylmannosamine kinase|UDP-GlcNAc-2-epimerase/ManAc kinase|UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GNE, check out the GNE Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GNE: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GNE/Glcne Antibody (A01647)
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No publications found for A01647
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