Product Info Summary
SKU: | A06163 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-GluR6 GRM6 Antibody
SKU/Catalog Number
A06163
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-GluR6 GRM6 Antibody (Catalog # A06163). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GluR6 GRM6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06163)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GluR6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06163 is reactive to GRM6 in Human, Mouse
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Calculated molecular weight
95468 MW
Background of mGluR6
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.
Inga Everts, J. Neurosci., Feb 1999; 19: 916.
Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 - 40173.
Sheng Yan, J. Neurosci., Jan 2004; 24: 679.
Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 - 17445.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06163 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
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Western blot analysis of extracts from HepG2 cells (Lane 2), using mGluR6 antiobdy A06163. The lane on the left is treated with synthesized peptide.
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Western blot analysis of extracts from mouse brain, using GluR6 antibody A06163.
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Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR6 antibody A06163.
Protein Target Info & Infographic
Gene/Protein Information For GRM6 (Source: Uniprot.org, NCBI)
Gene Name
GRM6
Full Name
Metabotropic glutamate receptor 6
Weight
95468 MW
Superfamily
G-protein coupled receptor 3 family
Alternative Names
Metabotropic glutamate receptor 6;mGluR6;GRM6;GPRC1F, MGLUR6; GRM6 CSNB1B, GPRC1F, MGLUR6, mGlu6 glutamate metabotropic receptor 6 metabotropic glutamate receptor 6|glutamate receptor, metabotropic 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GRM6, check out the GRM6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GRM6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GluR6 GRM6 Antibody (A06163)
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No publications found for A06163
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