Anti-Galectin-13 (GAL13) / Placental Protein 13 (PP13) Monoclonal Antibody

Product Name

Anti-Galectin-13 (GAL13) / Placental Protein 13 (PP13) Monoclonal Antibody

View all Galectin 13 Antibodies

SKU/Catalog Number

M08143-1

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-Galectin-13 (GAL13) / Placental Protein 13 (PP13) Monoclonal Antibody (Catalog # M08143-1). Tested in ELISA, IHC applications. This antibody reacts with Human.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-Galectin-13 (GAL13) / Placental Protein 13 (PP13) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M08143-1)

Host

Mouse

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Clonality

Monoclonal

Clone Number

Clone: PP13/1162

Isotype

IgG2b, kappa

Immunogen

Recombinant human Galectin-13 protein fragment (aa23-134)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M08143-1 is reactive to LGALS13 in Human

Reconstitution

Reconstitute with distilled water.

Observed Molecular Weight

68 kDa

Calculated molecular weight

16119 MW

Background of Galectin 13

This monoclonal antibody recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble -galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

M08143-1 is guaranteed for ELISA, IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ELISA (For coating, order antibody without BSA)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

Gene/Protein Information For LGALS13 (Source: Uniprot.org, NCBI)

Alternative Names

Galactoside-binding soluble lectin 13;Galectin-13;Gal-13;Placental tissue protein 13;PP13;Placental protein 13;LGALS13;PLAC8; LGALS13 GAL13, PLAC8, PP13 galectin 13 galactoside-binding soluble lectin 13|beta-galactoside-binding lectin|gal-13|lectin, galactoside-binding, soluble, 13|placental protein 13|placental tissue protein 13

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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