Product Info Summary
SKU: | A01453-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-Fes (K161) Antibody
SKU/Catalog Number
A01453-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Fes (K161) Antibody catalog # A01453-1. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Fes (K161) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01453-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Annexin I around the phosphorylation site of Y21.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01453-1 is reactive to FES in Human, Mouse, Rat
Applications
A01453-1 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
93497 MW
Background of FES
Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene
Janknecht R, et al. (1993) EMBO J. 12(13): 5097-5104.
Marais R, et al. (1993) Cell 73:381-393.
Kortenjann M, et al. (1994) Mol Cell Biol. 14:4815-4824.
Hill C S, et al. (1995) Cell. 80:199-211.
Cavigelli M, et al. (1995) EMBO J. 14:5957-5964.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
![a01453 1 anti fes k161 antibody ihc testing 1 a01453 1 anti fes k161 antibody ihc testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a01453-1-anti-fes-k161-antibody-ihc-testing-1.jpg)
Click image to see more details
Figure 1. Immunohistochemistry validation of FES using Anti-Fes (K161) Antibody (A01453-1).
Immunohistochemistry (IHC) analyzes of Fes (K161) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For FES (Source: Uniprot.org, NCBI)
Gene Name
FES
Full Name
Tyrosine-protein kinase Fes/Fps
Weight
93497 MW
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.10; EC 2.7.10.2; feline sarcoma oncogene; feline sarcoma virus; Fes; FPS; Proto-oncogene c-Fes; Proto-oncogene c-Fps; proto-oncogene tyrosine-protein kinase Fes/Fps; tyrosine-protein kinase Fes/Fps FES FPS FES proto-oncogene, tyrosine kinase tyrosine-protein kinase Fes/Fps|Oncogene FES, feline sarcoma virus|feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog|feline sarcoma oncogene|feline sarcoma/Fujinami avian sarcoma oncogene homolog|p93c-fes|proto-oncogene c-Fes|proto-oncogene c-Fps|proto-oncogene tyrosine-protein kinase Fes/Fps
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FES, check out the FES Infographic
![FES infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FES: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Fes (K161) Antibody (A01453-1)
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