Anti-EWSR1 Rabbit Monoclonal Antibody

Product Name

Anti-EWSR1 Rabbit Monoclonal Antibody

View all EWSR1 Antibodies

SKU/Catalog Number

M00589-2

Size

100 μl/vial

Form

Liquid

Description

Boster Bio Anti-EWSR1 Rabbit Monoclonal Antibody catalog # M00589-2. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EWSR1 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00589-2)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

21E99

Isotype

IgG

Immunogen

A synthesized peptide derived from human EWSR1

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00589-2 is reactive to EWSR1 in Human, Mouse, Rat

Applications

M00589-2 is guaranteed for IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

95 kDa

Calculated molecular weight

87058 MW

Background of EWSR1

Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Validation Images & Assay Conditions

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Western blot analysis of EWSR1 expression in K562 cell lysate.

Gene/Protein Information For EWSR1 (Source: Uniprot.org, NCBI)

Alternative Names

bK984G1.4; Ewing sarcoma breakpoint region 1 protein; Ewing sarcoma breakpoint region 1; Ewings sarcoma EWS-Fli1 (type 1) oncogene; EWS oncogene; EWSRNA-binding protein EWS EWSR1 EWS, EWS-FLI1, bK984G1.4 EWS RNA binding protein 1 RNA-binding protein EWS|EWS RNA-binding protein variant 6|Ewing sarcoma breakpoint region 1|Ewings sarcoma EWS-Fli1 (type 1) oncogene

For more info on EWSR1, check out the EWSR1 Infographic

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In this infographic, you will see the following information for EWSR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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