Anti-ERK5 MAPK7 Antibody

Product Name

Anti-ERK5 MAPK7 Antibody

View all ERK5/BMK1 Antibodies

SKU/Catalog Number

A02812

Size

100ul

Form

Liquid

Description

Boster Bio Anti-ERK5 MAPK7 Antibody catalog # A02812. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ERK5 MAPK7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02812)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human EphB1/2 around the phosphorylation site of Y594/604.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02812 is reactive to MAPK7 in Human, Mouse, Rat

Applications

A02812 is guaranteed for IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

88386 MW

Background of ERK5/BMK1

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.

Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For MAPK7 (Source: Uniprot.org, NCBI)

Alternative Names

Big MAP kinase 1; BMK1 kinase; BMK1; BMK-1; BMK1EC 2.7.11.24; EC 2.7.11; ERK5; ERK-5; ERK5MAPK 7; Extracellular signal-regulated kinase 5; extracellular-signal-regulated kinase 5; MAP kinase 7; MAPK7; mitogen-activated protein kinase 7; PRKM7ERK4 MAPK7 BMK1, ERK4, ERK5, PRKM7 mitogen-activated protein kinase 7 mitogen-activated protein kinase 7|BMK-1|BMK1 kinase|ERK-5|MAP kinase 7|MAPK 7|big MAP kinase 1|extracellular-signal-regulated kinase 5

For more info on MAPK7, check out the MAPK7 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAPK7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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