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MAPK7 Antibodies
AND MAPK7 ELISA kits, MAPK7 Proteins
Many biological assays use antibodies to detect MAPK7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAPK7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAPK7 antibodies...
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MAPK7 Infographic by Boster Bio
All MAPK7 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M02812
100 μl
Cat # M02812
100 μl
Anti-ERK5/MAPK7 Antibody Picoband®
2 Citations
Human, Monkey, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A02812-3
100 μg/vial
Cat # A02812-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, WB
$523
Cat # M02812-1
100 µl
Cat # M02812-1
100 µl
MAPK7 Overview
Facts about Mitogen-activated protein kinase 7.
Mitogen-activated protein kinase 7 (MAPK7)
The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C.
EGF activates MAPK7 through a Ras- independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation.
Gene Information
| Human | |
|---|---|
| Gene Name: | MAPK7 |
| Uniprot: | Q13164 |
| Entrez: | 5598 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
Big MAP kinase 1; BMK1 kinase; BMK1; BMK-1; BMK1EC 2.7.11.24; EC 2.7.11; ERK5; ERK-5; ERK5MAPK 7; Extracellular signal-regulated kinase 5; extracellular-signal-regulated kinase 5; MAP kinase 7; MAPK7; mitogen-activated protein kinase 7; PRKM7ERK4
Molecular Weight
Mass (kDA):
88.386 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p11.2 |
| Sequence: | 17; NC_000017.11 (19377721..19383544) |
Tissue Specificity
Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.
Subcellular Localizations
Cytoplasm. Nucleus. Nucleus, PML body. Translocates to the nucleus upon activation.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Cell Transformation, Neoplastic
- Bone Neoplasms
- Osteosarcoma
- Aneurysm
- Adult Acute Lymphocytic Leukemia
- Tumor Progression
- Uterine Cervical Neoplasm
- Leukemia, T-cell
- Intracranial Aneurysm
Interacting Proteins
- MAP2K5
- PML
Pathways
- Cell Proliferation
- Cell Cycle
- Cell Growth
- Regeneration
- Cell Division
- Stem Cell Proliferation
- Cell Motility
- Mitosis
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAPK7
bosterbio.com/bosterbio-gene-info-cards/MAPK7
References
PMID: 7646528 by Lee J.-D., et al. Primary structure of BMK1: a new mammalian map kinase.
PMID: 7759517 by Zhou G., et al. Components of a new human protein kinase signal transduction pathway.
3 Publications of Boster MAPK7 Antibodies & ELISA Kits
- PubMed ID: 10.1155/2021/6431007, Effects of the Wenyang Zhenshuai Granule on the Expression of LncRNA-MiR143HG/mi...
- PubMed ID: -, Mehrdoost, S., Yaghmaei, P., Jafary, H., Ebrahim-Habibi, A. (2021). The therapeu...
- PubMed ID: 29594152, Vu HT, Kotla S, Ko KA, Fujii Y, Tao Y, Medina J, Thomas T, Hada M, Sood AK, Sing...
*More publications can be found for each product on its corresponding product page