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Product Info Summary
| SKU: | A07731 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-DMGDH Antibody
SKU/Catalog Number
A07731
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-DMGDH Antibody (Catalog # A07731). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-DMGDH Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07731)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human DMGDH.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07731 is reactive to DMGDH in Human
Reconstitution
Calculated molecular weight
96811 MW
Background of DMGDH
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Binzak B.A., Mol. Genet. Metab. 69:181-187(2000).
Binzak B.A., Am. J. Hum. Genet. 68:839-847(2001).
Moolenaar S.H., Clin. Chem. 45:459-464(1999)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07731 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
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Western blot analysis of extracts from HT-29 cells and A549 cells, using DMGDH antibody A07731.
Protein Target Info & Infographic
Gene/Protein Information For DMGDH (Source: Uniprot.org, NCBI)
Gene Name
DMGDH
Full Name
Dimethylglycine dehydrogenase, mitochondrial
Weight
96811 MW
Superfamily
GcvT family
Alternative Names
Dimethylglycine dehydrogenase, mitochondrial;1.5.8.4;ME2GLYDH;DMGDH; DMGDH DMGDHD, ME2GLYDH dimethylglycine dehydrogenase dimethylglycine dehydrogenase, mitochondrial
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DMGDH, check out the DMGDH Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DMGDH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DMGDH Antibody (A07731)
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No publications found for A07731
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