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DMGDH Antibodies
AND DMGDH ELISA kits, DMGDH Proteins
Many biological assays use antibodies to detect DMGDH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DMGDH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DMGDH antibodies...
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DMGDH Overview
Facts about Dimethylglycine dehydrogenase, mitochondrial.
Dimethylglycine dehydrogenase, mitochondrial (DMGDH)
Catalyzes the demethylation of N,N-dimethylglycine into sarcosine.
Also has action with sarcosine in vitro..
Gene Information
| Human | |
|---|---|
| Gene Name: | DMGDH |
| Uniprot: | Q9UI17 |
| Entrez: | 29958 |
Family
| Belongs to: |
|---|
| GcvT family |
Alternative Names
dimethylglycine dehydrogenase; dimethylglycine dehydrogenase, mitochondrial; DMGDHD; EC 1.5.99.2; ME2GLYDH
Molecular Weight
Mass (kDA):
96.811 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q14.1 |
| Sequence: | 5; NC_000005.10 (78997564..79069674, complement) |
Subcellular Localizations
Mitochondrion.
Diseases
- Inborn Errors Of Metabolism
- Heart Diseases
- Liver Diseases
- Chronic Infectious Disease
- Liver Carcinoma
- Hepatitis
- Heart Failure
- Cleft Palate
- Hypoxia
- Hepatitis B
- Cardiomyopathy, Dilated
- Medium-chain Acyl-coenzyme A Dehydrogenase Deficiency
- Hypokinesia
Pathways
- Demethylation
- Oxidative Demethylation
- Cell Death
- Transport
- Translation
- Electron Transport
- Electron Transport Chain
PTMs
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DMGDH
bosterbio.com/bosterbio-gene-info-cards/DMGDH
References
PMID: 10767172 by Binzak B.A., et al. Structure and analysis of the human dimethylglycine dehydrogenase gene.
PMID: 11231903 by Binzak B.A., et al. Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.