Key=store_id
Key=entity_id, value=75411
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Key=type_id, value=simple
Key=sku, value=A03671
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2020-03-11 06:18:47
Key=updated_at, value=2024-09-26 01:02:48
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-DFF45 DFFA Antibody
Key=cj_search_index
Key=publication_count, value=0
Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=conjugate
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Rabbit
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1371
Key=yoast_content_score, value=60
Key=price, value=449.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-DFF45 DFFA Antibody
Key=meta_description, value=Boster Bio Anti-DFF45 DFFA Antibody (Catalog # A03671). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human. Supplied as 0.1 mg in Liquid form antibody.
Key=image, value=no_selection
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Key=url_key, value=anti-dff45-dffa-antibody-a03671-boster
Key=url_path, value=anti-il-8-antibody-a00423-boster
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Key=msrp_display_actual_price_type, value=Use config
Key=gift_message_available, value=No
Key=size, value=0.1 mg
Key=protein_name, value=DNA fragmentation factor, 45kDa, alpha polypeptide
Key=gene_full_name, value=DNA fragmentation factor, 45kDa, alpha polypeptide
Key=uniprot_id, value=O00273
Key=sensitivity
Key=applications, value=ELISA, IF, ICC, WB
Key=reactivity, value=Human
Key=form, value=Liquid
Key=concentration, value=1 mg/ml
Key=cross_reactivity, value=At least three isoforms of KIF5 are known to exist; this antibody will recognize all three isoforms.
Key=clone_number
Key=predicted_reactivity, value=Mouse
Key=source_company, value=Prosci 1141; Cost: 249
Key=isotype, value=IgG
Key=molecular_weight, value=36522 MW
Key=sample_size_available, value=25ug for $99, contact us for details
Key=related_product_skus, value=EK0413,PB9621,PROTP10145,PROTP10145-1,PROTP10145-2,PROTP10145-3,PROTP19874,PROTP26894,PROTP41324,PROTP67813
Key=product_category, value=Primary Antibodies
Key=research_category, value=Apoptosis
Key=clonality, value=Polyclonal
Key=swatch_image, value=no_selection
Key=rating_value, value=100
Key=review_count, value=6
Key=mp_exclude_sitemap, value=No
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Key=cj_related_products, value=Apoptotic Dna Fragmentation:M01044|A01044-2^Epithelial Cell Proliferation:EK1524|EK1564^Hepatic Ischaemia:A05829-3|A01884
Key=description, value=Boster Bio Anti-DFF45 DFFA Antibody (Catalog # A03671). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Key=short_description, value=Boster Bio Anti-DFF45 DFFA Antibody (Catalog # A03671). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Key=meta_keyword, value=Anti-DFF45 DFFA Antibody
Key=contents, value=DFF45 Antibody is supplied in PBS containing 0.02% sodium azide.
Key=background, value=Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A human 45 kDa DNA fragmentation factor (DFF45) was identified recently which was cleaved by caspase-3 during apoptosis. Mouse homologue of human DFF45 was identified as a DNase inhibitor designated ICAD. Upon cleavage of DFF45/ICAD, a caspase activated deoxyribonuclease (DFF40/CAD) is released and activated and eventually causes the degradation of DNA in the nuclei. Therefore, the cleavage of DFF45/ICAD, which causes DFF40/CAD activation and DNA degradation, is the hallmark of apoptotic cell death.
Key=gene_name, value=DFFA
Key=synonyms, value=DFF1, ICAD, DFF-45, DFF1, DFF45, H13, DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit
Key=application_details, value=DFF45 antibody can be used for detection of DFF45 and one of the cleaved fragments of DFF45 by Western blot at at 0.5 - 1 μg/mL and for immunoprecipitation. A 45 kDa band can be detected in non-apoptotic cells. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Key=subcellular_localization, value=Cytoplasm.
Key=tissue_specificity, value=Isoform 1 is found in both brain and placenta.
Key=protein_function, value=Inhibitor of the caspase-activated DNase (DFF40).
Key=application_notes
Key=description_before_attributes
Key=competitor_equivalent_skus, value=sc 25342|sc 55462|sc 7165|sc 4600|sc 73321|sc 7922|sc 1269|sc 376750|sc 8427|sc 7302|sc 52870|sc 101499|sc 32817|sc 71367
Key=immunogen, value=DFF45 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DFF45. The immunogen is located within the last 50 amino acids of DFF45.
Key=purification, value=DFF45 Antibody is Antibody is DEAE purified.
Key=storage, value=DFF45 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Key=custom_attribute_1, value=68 kDa
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