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- Table of Contents
Facts about DNA fragmentation factor subunit alpha.
Inhibitor of the caspase-activated DNase (DFF40).
.Human | |
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Gene Name: | DFFA |
Uniprot: | O00273 |
Entrez: | 1676 |
Belongs to: |
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No superfamily |
DFF1; DFF1DNA fragmentation factor 45 kDa subunit; DFF45; DFF45DNA fragmentation factor subunit alpha; DFF-45DNA fragmentation factor, 45 kD, alpha polypeptide; DFFA; DNA fragmentation factor, 45kDa, alpha polypeptide; ICAD; Inhibitor of CAD
Mass (kDA):
36.522 kDA
Human | |
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Location: | 1p36.22 |
Sequence: | 1; NC_000001.11 (10456522..10472529, complement) |
Cytoplasm.
PMID: 9108473 by Liu X., et al. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.
PMID: 10409614 by Gu J.J., et al. Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40.