Anti-Coatomer subunit zeta-1 COPZ1 Antibody

Product Name

Anti-Coatomer subunit zeta-1 COPZ1 Antibody

View all COPZ1 Antibodies

SKU/Catalog Number

A07977

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Coatomer subunit zeta-1 COPZ1 Antibody (Catalog # A07977). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Coatomer subunit zeta-1 COPZ1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07977)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human COPZ1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A07977 is reactive to COPZ1 in Human, Mouse

Reconstitution

Calculated molecular weight

20198 MW

Background of COPZ1

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors By similarity.The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

Futatsumori M., J. Biochem. 128:793-801(2000).
Lai C.-H., Genome Res. 10:703-713(2000).
Zhang Q.-H., Genome Res. 10:1546-1560(2000)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A07977 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

Gene/Protein Information For COPZ1 (Source: Uniprot.org, NCBI)

Alternative Names

Coatomer subunit zeta-1;Zeta-1-coat protein;Zeta-1 COP;COPZ1;COPZ;CGI-120, HSPC181; COPZ1 CGI-120, COPZ, HSPC181, zeta-COP, zeta1-COP COPI coat complex subunit zeta 1 coatomer subunit zeta-1|coatomer protein complex subunit zeta 1|coatomer protein complex, subunit zeta|zeta-1 COP|zeta-1-coat protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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