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- Table of Contents
Facts about Coatomer subunit zeta-1.
In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). .
Human | |
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Gene Name: | COPZ1 |
Uniprot: | P61923 |
Entrez: | 22818 |
Belongs to: |
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adaptor complexes small subunit family |
Coatomer subunit zeta-1
Mass (kDA):
20.198 kDA
Human | |
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Location: | 12q13.13 |
Sequence: | 12; NC_000012.12 (54325109..54351850) |
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
PMID: 11056392 by Futatsumori M., et al. Identification and characterization of novel isoforms of COP I subunits.
PMID: 19167404 by Yu W., et al. Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats.