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Product Info Summary
| SKU: | M09548 |
|---|---|
| Size: | 100ug/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | IF, IHC |
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Product info
Product Name
Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody
View all beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibodies
SKU/Catalog Number
M09548
Size
100ug/vial
Form
Liquid
Description
Boster Bio Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody (Catalog # M09548). Tested in IF, IHC applications. This antibody reacts with Human.
Storage & Handling
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Cite This Product
Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M09548)
Host
Mouse
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Clonality
Monoclonal
Clone Number
Clone: NK/804
Isotype
IgM, kappa
Immunogen
Membrane antigen from HSB-2 cells
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M09548 is reactive to B3GAT1 in Human
Reconstitution
Reconstitute with distilled water.
Observed Molecular Weight
68 kDa
Calculated molecular weight
38256 MW
Background of beta-1,3-Glucuronyltransferase 1/B3GAT1
Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M09548 is guaranteed for IF, IHC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Validation Images & Assay Conditions
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Formalin-fixed, paraffin-embedded human Tonsil stained with Anti-CD57 Monoclonal Antibody (NK/804).
Protein Target Info & Infographic
Gene/Protein Information For B3GAT1 (Source: Uniprot.org, NCBI)
Gene Name
B3GAT1
Full Name
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
Weight
38256 MW
Superfamily
glycosyltransferase 43 family
Alternative Names
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1;2.4.1.135;Beta-1,3-glucuronyltransferase 1;Glucuronosyltransferase P;GlcAT-P;UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase;GlcUAT-P;B3GAT1;GLCATP; B3GAT1 CD57, GLCATP, GLCUATP, HNK1, LEU7, NK-1, NK1 beta-1,3-glucuronyltransferase 1 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1|LEU7 |UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase|glucuronosyltransferase P
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on B3GAT1, check out the B3GAT1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for B3GAT1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody (M09548)
Hello CJ!
M09548 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody
Question
We are currently using anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal antibody M09548 for human tissue, and we are well pleased with the IHC results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on horse tissues as well?
J. Wu
Verified customer
Asked: 2018-05-22
Answer
The anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal antibody (M09548) has not been validated for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2018-05-22
