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Product Info Summary
| SKU: | A07385 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Cartilage matrix protein MATN1 Antibody
View all Matrilin-1 Antibodies
SKU/Catalog Number
A07385
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Cartilage matrix protein MATN1 Antibody (Catalog # A07385). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
MATN1 antibody can be stored at 4˚C, stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Cartilage matrix protein MATN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07385)
Host
Rabbit
Contents
MATN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MATN1 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN1. The immunogen is located within amino acids 370 - 420 of MATN1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
LANCL2 antibody is human, mouse and rat reactive.
Reactive Species
A07385 is reactive to MATN1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
53701 MW
Background of Matrilin-1
Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07385 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MATN1 antibody can be used for detection of MATN1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MATN1 in rat liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of MATN1 in human liver tissue with MATN1 antibody at 5 μg/mL.
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Immunofluorescence of MATN1 in Human Liver cells with MATN1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For MATN1 (Source: Uniprot.org, NCBI)
Gene Name
MATN1
Full Name
Cartilage matrix protein
Weight
53701 MW
Alternative Names
CMP, CRTM, CMP, Cartilage matrix protein, Matrilin-1 MATN1 CMP, CRTM matrilin 1 cartilage matrix protein|matrilin 1, cartilage matrix protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MATN1, check out the MATN1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MATN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cartilage matrix protein MATN1 Antibody (A07385)
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