Anti-Calsequestrin 1 CASQ1 Antibody

Product Name

Anti-Calsequestrin 1 CASQ1 Antibody

View all Calsequestrin 1 Antibodies

SKU/Catalog Number

A05235

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Calsequestrin 1 CASQ1 Antibody catalog # A05235. Tested in WB,IHC,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Calsequestrin 1 CASQ1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05235)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human K1C12 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05235 is reactive to CASQ1 in Human, Mouse, Rat

Applications

A05235 is guaranteed for Flow Cytometry, IHC, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

45160 MW

Background of Calsequestrin 1

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Jenny J. Tong, Nucleic Acids Res., Mar 2002; 30: 1114 - 1123.
Hung-Ying Kao, J. Biol. Chem., Jan 2002; 277: 187 - 193.
Denise D. Fischer, J. Biol. Chem., Feb 2002; 277: 6656 - 6666.
Matthew H. Brush, J. Biol. Chem., Feb 2004; 279: 7685 - 7691.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500
IHC: 1:50-1:200
FC: 1:50-1:100

Validation Images & Assay Conditions

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Figure 1. Immunohistochemistry validation of CASQ1 using Anti-Calsequestrin 1 CASQ1 Antibody (A05235).

Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-Calsequestrin 1 antibody. Counter stained with hematoxylin.
For more protocol information of IHC

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Figure 2. Immunohistochemistry validation of CASQ1 using Anti-Calsequestrin 1 CASQ1 Antibody (A05235).

Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-Calsequestrin 1 antibody. Counter stained with hematoxylin.
For more protocol information of IHC

Gene/Protein Information For CASQ1 (Source: Uniprot.org, NCBI)

Alternative Names

calmitin; calmitine; calsequestrin 1 (fast-twitch, skeletal muscle); Calsequestrin, skeletal muscle isoform; calsequestrin-1; CASQ; PDIB1 CASQ1 CASQ, PDIB1, VMCQA calsequestrin 1 calsequestrin-1|calmitin|calmitine|calsequestrin 1 (fast-twitch, skeletal muscle)

For more info on CASQ1, check out the CASQ1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CASQ1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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