Data

Array ( [0] => store_id [1] => entity_id [2] => attribute_set_id [3] => type_id [4] => sku [5] => has_options [6] => required_options [7] => created_at [8] => updated_at [9] => mst_search_weight [10] => status [11] => name [12] => cj_search_index [13] => publication_count [14] => qty_in_warehouses [15] => is_recurring [16] => visibility [17] => tax_class_id [18] => featured [19] => featured_image [20] => fb_product [21] => custom_product_page [22] => free_shipping [23] => template [24] => host [25] => googleshopping_exclude [26] => yoast_keyword_score [27] => yoast_content_score [28] => badge [29] => price [30] => weight [31] => meta_title [32] => meta_description [33] => image [34] => small_image [35] => thumbnail [36] => gallery [37] => url_key [38] => url_path [39] => options_container [40] => image_label [41] => small_image_label [42] => thumbnail_label [43] => msrp_display_actual_price_type [44] => gift_message_available [45] => size [46] => protein_name [47] => gene_full_name [48] => uniprot_id [49] => reconstitution [50] => sensitivity [51] => applications [52] => reactivity [53] => form [54] => concentration [55] => clone_number [56] => predicted_reactivity [57] => source_company [58] => isotype [59] => molecular_weight [60] => sample_size_available [61] => related_product_skus [62] => product_category [63] => research_category [64] => clonality [65] => swatch_image [66] => rating_value [67] => review_count [68] => phospho_site [69] => mp_exclude_sitemap [70] => yoast_facebook_image [71] => yoast_twitter_image [72] => cj_related_products [73] => description [74] => short_description [75] => meta_keyword [76] => contents [77] => background [78] => gene_name [79] => synonyms [80] => kit_components [81] => application_details [82] => subcellular_localization [83] => tissue_specificity [84] => protein_function [85] => application_notes [86] => competitor_equivalent_skus [87] => immunogen [88] => purification [89] => storage [90] => reproducibility [91] => custom_attribute_1 [92] => custom_attribute_3 [93] => options [94] => media_gallery [95] => extension_attributes [96] => tier_price [97] => tier_price_changed [98] => category_ids [99] => quantity_and_stock_status [100] => is_salable [101] => website_ids [102] => request_path [103] => rating_summary [104] => _cache_instance_store_filter [105] => media_gallery_images )
Key=store_id
Key=entity_id, value=35011
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=M00223
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2017-04-28 21:59:04
Key=updated_at, value=2024-10-25 05:01:30
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-BRG1 Rabbit Monoclonal Antibody
Key=cj_search_index
Key=publication_count, value=0
Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Rabbit
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1369
Key=yoast_content_score, value=60
Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-BRG1 Rabbit Monoclonal Antibody (M00223) | Bosterbio
Key=meta_description, value=Boster Bio Anti-BRG1 Rabbit Monoclonal Antibody catalog # M00223. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Key=image, value=/m/0/m00223-wb7.jpg
Key=small_image, value=/m/0/m00223-wb8.jpg
Key=thumbnail, value=/m/0/m00223-wb.jpg
Key=gallery, value=/A00237_1.jpg:/A00237_2.jpg:/A00237_3.jpg
Key=url_key, value=anti-brg1-rabbit-monoclonal-antibody-m00223-boster
Key=url_path, value=anti-brg1-rabbit-monoclonal-antibody-m00223-boster
Key=options_container, value=Product Info Column
Key=image_label, value=All lanes use the Antibody at 1:3W dilution for 1 hour at room temperature.
Key=small_image_label, value=All lanes use the Antibody at 1:3W dilution for 1 hour at room temperature.
Key=thumbnail_label, value=Western blot analysis of BRG1 expression in HeLa cell lysate.
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=100 μl
Key=protein_name, value=P2X purinoceptor 1
Key=gene_full_name, value=Transcription activator BRG1
Key=uniprot_id, value=P51532
Key=reconstitution, value=Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Key=sensitivity
Key=applications, value=IP, IF, IHC, ICC, WB
Key=reactivity, value=Human, Mouse, Rat
Key=form, value=Liquid
Key=concentration, value=Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Key=clone_number, value=GFB-19
Key=predicted_reactivity
Key=source_company, value=Boster Amways (order through China) CY5794, Cost 100ul 580RMB, 30ul 210RMB
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=184646 MW
Key=sample_size_available, value=30ul for $99, contact us for details
Key=related_product_skus, value=PROTP51532
Key=product_category, value=Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies
Key=research_category, value=Neurodegenerative Disease, Neurology Process, Neuroscience
Key=clonality, value=Monoclonal
Key=swatch_image, value=/antibody/ek0660-2-ELISA-mouse-axl-picokine-elisa-kit.jpg
Key=rating_value, value=100
Key=review_count, value=10
Key=phospho_site
Key=mp_exclude_sitemap, value=Yes
Key=yoast_facebook_image, value=no_selection
Key=yoast_twitter_image, value=no_selection
Key=cj_related_products, value=Atp-dependent Chromatin Remodeling:M00223-1^Rhabdoid Tumor:A00223-1|M00223-1|A00223|M00223-2|EKC2609
Key=description, value=Boster Bio Anti-BRG1 Rabbit Monoclonal Antibody catalog # M00223. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Key=short_description, value=Boster Bio Anti-BRG1 Rabbit Monoclonal Antibody catalog # M00223. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Key=meta_keyword, value=Anti-LRRK2 Rabbit Monoclonal Antibody
Key=contents, value=Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Key=background
Key=gene_name, value=SMARCA4
Key=synonyms, value=Transcription activator BRG1;3.6.4.-;ATP-dependent helicase SMARCA4;BRG1-associated factor 190A;BAF190A;Mitotic growth and transcription activator;Protein BRG-1;Protein brahma homolog 1;SNF2-beta;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4;SMARCA4;BAF190A, BRG1, SNF2B, SNF2L4;
Key=kit_components, value=-
Key=application_details, value=WB 1:5000-1:20000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
Key=subcellular_localization, value= Nucleus .
Key=tissue_specificity, value= Colocalizes with ZEB1 in E-cadherin-negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level). .
Key=protein_function, value= Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron- specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. SMARCA4/BAF190A may promote neural stem cell self- renewal/proliferation by enhancing Notch-dependent proliferative signals, while concurrently making the neural stem cell insensitive to SHH-dependent differentiating cues (By similarity). Acts as a corepressor of ZEB1 to regulate E-cadherin transcription and is required for induction of epithelial-mesenchymal transition (EMT) by ZEB1. .
Key=application_notes, value=Specific for endogenous levels of the ~100 kDa GluR1 protein phosphorylated at Ser845. Immunolabeling is completely eliminated by treatment with λ-phosphatase.
Key=competitor_equivalent_skus, value=sc 165863|sc 165862|sc 292072|sc 165861|sc 101493|sc 390197|sc 390231|sc 390211
Key=immunogen, value=A synthesized peptide derived from human BRG1
Key=purification, value=Affinity-chromatography
Key=storage, value=Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Key=reproducibility, value=-
Key=custom_attribute_1, value=58 kDa
Key=custom_attribute_3, value=BM4631
Key=options
Key=media_gallery
Key=extension_attributes
Key=tier_price
Key=tier_price_changed
Key=category_ids
Key=quantity_and_stock_status
Key=is_salable
Key=website_ids
Key=request_path
Key=rating_summary
Key=_cache_instance_store_filter
Key=media_gallery_images