Key=store_id
Key=entity_id, value=54723
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=EKC2287
Key=has_options, value=0
Key=required_options, value=0
Key=created_at, value=2019-02-12 00:21:01
Key=updated_at, value=2024-09-26 01:01:54
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=GRB10 (Phospho-Tyr67) Colorimetric Cell-Based ELISA Kit
Key=cj_search_index
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Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=cell-based-phospho-elisa-kits
Key=price, value=540.0000
Key=weight, value=1.0000
Key=meta_title, value=GRB10 (Phospho-Tyr67) Colorimetric Cell-Based ELISA Kit Price
Key=meta_description, value=GRB10 (Phospho-Tyr67) Colorimetric Cell-Based ELISA Kit EKC2287
Key=image, value=/b/o/boster-box.png
Key=small_image, value=/b/o/boster-box.png
Key=thumbnail, value=/b/o/boster-box.png
Key=url_key, value=grb10-phospho-tyr67-colorimetric-cell-based-elisa-kit-ekc2287-boster
Key=url_path, value=grb10-phospho-tyr67-colorimetric-cell-based-elisa-kit-ekc2287-boster
Key=options_container, value=Product Info Column
Key=image_label, value=Boster Kit Box
Key=small_image_label, value=Boster Kit Box
Key=thumbnail_label, value=Boster Kit Box
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=1 kit, containing two 96-well plates and all necessary reagents
Key=gene_full_name, value=Growth factor receptor-bound protein 10
Key=uniprot_id, value=Q13322
Key=assay_range, value=> 5000 cells/well
Key=applications, value=ELISA
Key=reactivity, value=Human
Key=source_company, value=AssayBiotech CBP1406; Cost: 300
Key=molecular_weight, value=67231 MW
Key=product_category, value=Cell-Based ELISA Kits
Key=rating_value, value=97.6
Key=review_count, value=5
Key=mp_exclude_sitemap, value=No
Key=cj_related_products, value=Beckwith-wiedemann Syndrome:PB9937|PA2182^Benign Mixed Epithelial And Stromal Tumor Of Kidney:A03338^Regulation Of Growth:A01823-2|PB9512^Russell-silver Syndrome:A03240
Key=description, value=The GRB10 (Phospho-Tyr67) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GRB10 (Phospho-Tyr67) protein expression profile in cells. The kit can be used for measuring the relative amounts of GRB10 (Phospho-Tyr67) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GRB10 (Phospho-Tyr67).
Key=short_description, value=The GRB10 (Phospho-Tyr67) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GRB10 (Phospho-Tyr67) protein expression profile in cells. The kit can be used for measuring the relative amounts of GRB10 (Phospho-Tyr67) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GRB10 (Phospho-Tyr67).
Key=gene_name, value=GRB10
Key=synonyms, value=GRB10 adaptor protein;GRBIR;Growth factor receptor-bound protein 10;Insulin receptor binding protein GRB-IR;KIAA0207
Key=sample_type, value=Cell lines
Key=kit_components, value=GRB10 (Phospho-Tyr67)
Key=subcellular_localization, value=Cytoplasm. When complexed with NEDD4 and IGF1R, follows IGF1R internalization, remaining associated with early endosomes. Uncouples from IGF1R-containing endosomes before the sorting of the receptor to the lysosomal compartment (By similarity).
Key=tissue_specificity, value=Widely expressed in fetal and adult tissues, including fetal and postnatal liver, lung, kidney, skeletal muscle, heart, spleen, skin and brain.
Key=protein_function, value= Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin- stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin- stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2.
Key=storage, value=Store at 4°C for up to 6 months.
Key=custom_attribute_1, value=GRB10
Key=custom_attribute_2, value=Phospho-Tyr67
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