GFRA3 Antibodies

AND GFRA3 ELISA kits, GFRA3 Proteins

Many biological assays use antibodies to detect GFRA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GFRA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GFRA3 antibodies...

We validate the specificity of these antibodies to GFRA3 by testing them on tissues known to express GFRA3 positively and negatively. Browse below to find the GFRA3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GFRA3 Infographic by Boster Bio

All GFRA3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human GFRA3 ELISA Kit PicoKine®

7 Q&As

Human

ELISA

$499
Cat # EK2075
96 wells/kit, with removable strips.

Mouse GFRA3 ELISA Kit PicoKine®

10 Q&As

Mouse

ELISA

$499
Cat # EK2076
96 wells/kit, with removable strips.

Anti-GFR alpha 3 Gfra3 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A07481
0.1 mg

Human GFR alpha-3 Recombinant Protein

SDS-PAGE

$350
Cat # PROTO60609
Starting from 10ug

GFR alpha 3 (GFRA3) (NM_001496) Human Over-expression Lysate

Human

$628
Cat # LS002676
100 µg

GFRA3 Overview

Facts about GDNF family receptor alpha-3.

GFRA3 3D structure. Source: alphafold

GDNF family receptor alpha-3 (GFRA3)

Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.

Gene Information

Human
Gene Name:	GFRA3
Uniprot:	O60609
Entrez:	2676

Family

Belongs to:

GDNFR family

Alternative Names

GDNF family receptor alpha 3; GDNF family receptor alpha-3; GDNF R alpha-3; GDNF receptor alpha-3; GDNFR-alpha-3; GFR alpha3; GFR alpha-3; GFRA3; GFRa-3; GFR-alpha-3; glial cell line-derived neurotrophic factor receptor alpha-3; GPI-linked receptor

Molecular Weight

Mass (kDA):
44.511 kDA

Genomic Context


Human

Location:	5q31.2
Sequence:	5; NC_000005.10 (138252380..138274621, complement)

Tissue Specificity

Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. Very low or no expression detected in the hematopoietic system.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Nervousness
Carcinoma
Neoplasms
Neoplasm Invasiveness
Pain
Medullary Carcinoma Of Thyroid
Thyroid Neoplasm
Cell Invasion
Nerve Damage
Malignant Neoplasm Of Thyroid
Neoplasm Metastasis
Brain Ischemia
Malignant Neoplasms

Congenital Absence
Ischemia
Malignant Paraganglionic Neoplasm
Hyperalgesia
Peripheral Neuropathy
Neurodegenerative Disorders
Numbness

Interacting Proteins

ARTN

Pathways

Localization
Transport
Aging
Hypersensitivity
System Development
Cell Proliferation
Regeneration
Nervous System Development
Innervation
Brain Development
Neurogenesis
Reverse Transcription
Swimming

Mrna Transcription
Translation
Blastocyst Development
Peripheral Nervous System Development
Peyer's Patch Development
Enteric Nervous System Development
Glycosylation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GFRA3

References

PMID: 9576965 by Baloh R.H., et al. GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family.

PMID: 9883723 by Baloh R.H., et al. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex.