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- Table of Contents
1 Citations
Facts about CCN family member 2.
Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Human | |
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Gene Name: | CCN2 |
Uniprot: | P29279 |
Entrez: | 1490 |
Belongs to: |
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CCN family |
CCN family member 2
Mass (kDA):
38.091 kDA
Human | |
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Location: | 6q23.2 |
Sequence: | 6; NC_000006.12 (131948176..131951372, complement) |
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Secreted, extracellular space, extracellular matrix. Secreted.
PMID: 1654338 by Bradham D.M., et al. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.
PMID: 1293144 by Igarashi A., et al. Connective tissue growth factor.
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