Product Info Summary
SKU: | PROTP35916 |
---|---|
Size: | 2ug, 10ug, 1mg |
Origin Species: | Human |
Source: | Insect cells |
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Product info
Product Name
FLT4 Vascular Endothelial Growth Factor Receptor-3 Human Recombinant Protein
View all VEGFR3/Flt-4 recombinant proteins
SKU/Catalog Number
PROTP35916
Size
2ug, 10ug, 1mg
Description
Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25-774 amino acids and having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques.
Storage & Handling
Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Cite This Product
FLT4 Vascular Endothelial Growth Factor Receptor-3 Human Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP35916)
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
FLT4 was lyophilized from a concentrated (1mg/ml) sterile solution containing 1xPBS.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Predicted MW
152.757kDa
Reconstitution
It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 µg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml.
Assay dilution & Images
Reconstitution
It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Validation Images & Assay Conditions
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Recombinant protein fun image
Protein Target Info & Infographic
Gene/Protein Information For FLT4 (Source: Uniprot.org, NCBI)
Gene Name
FLT4
Full Name
Vascular endothelial growth factor receptor 3
Weight
152.757kDa
Superfamily
protein kinase superfamily
Alternative Names
Tyrosine-protein kinase receptor FLT4; PCL; FLT41; FMS-LIKE TYROSINE KINASE 4; VEGFR-3; VEGFR3 FLT4 CHTD7, FLT-41, LMPH1A, LMPHM1, PCL, VEGFR-3, VEGFR3, FLT4 fms related receptor tyrosine kinase 4 vascular endothelial growth factor receptor 3|Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4|VEGF receptor-3|fms related tyrosine kinase 4|fms-like tyrosine kinase 4|primary congenital lymphedema|tyrosine-protein kinase receptor FLT4
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on FLT4, check out the FLT4 Infographic
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In this infographic, you will see the following information for FLT4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For FLT4 Vascular Endothelial Growth Factor Receptor-3 Human Recombinant Protein (PROTP35916)
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