FLT4 Vascular Endothelial Growth Factor Receptor-3 Human Recombinant Protein

VEGFR3/Flt-4 protein, Human

Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25-774 amino acids and having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques.

Product Info Summary

SKU: PROTP35916
Size: 2ug, 10ug, 1mg
Origin Species: Human
Source: Insect cells

Product Name

FLT4 Vascular Endothelial Growth Factor Receptor-3 Human Recombinant Protein

View all VEGFR3/Flt-4 recombinant proteins

SKU/Catalog Number

PROTP35916

Size

2ug, 10ug, 1mg

Description

Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25-774 amino acids and having a total molecular mass of 120 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The FLT4 is purified by proprietary chromatographic techniques.

Storage & Handling

Lyophilized FLT4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Cite This Product

FLT4 Vascular Endothelial Growth Factor Receptor-3 Human Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP35916)

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

FLT4 was lyophilized from a concentrated (1mg/ml) sterile solution containing 1xPBS.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Predicted MW

152.757kDa

Reconstitution

It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5 µg/ml can bind recombinant rat VEGF-C in a linear range of 8-500 ng/ml.

Reconstitution

It is recommended to reconstitute the lyophilized FLT4 in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Validation Images & Assay Conditions

Gene/Protein Information For FLT4 (Source: Uniprot.org, NCBI)

Gene Name

FLT4

Full Name

Vascular endothelial growth factor receptor 3

Weight

152.757kDa

Superfamily

protein kinase superfamily

Alternative Names

Tyrosine-protein kinase receptor FLT4; PCL; FLT41; FMS-LIKE TYROSINE KINASE 4; VEGFR-3; VEGFR3 FLT4 CHTD7, FLT-41, LMPH1A, LMPHM1, PCL, VEGFR-3, VEGFR3, FLT4 fms related receptor tyrosine kinase 4 vascular endothelial growth factor receptor 3|Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4|VEGF receptor-3|fms related tyrosine kinase 4|fms-like tyrosine kinase 4|primary congenital lymphedema|tyrosine-protein kinase receptor FLT4

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on FLT4, check out the FLT4 Infographic

FLT4 infographic

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In this infographic, you will see the following information for FLT4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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Total: $250

SKU:PROTP35916

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