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Product Info Summary
| SKU: | PROTP00451 |
|---|---|
| Size: | 250IU, 500IU, 1000IU |
| Origin Species: | Human |
| Source: | CHO cells |
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Product info
Product Name
F8 Coagulation Factor-VIII Human Recombinant Protein
View all F8 recombinant proteins
SKU/Catalog Number
PROTP00451
Size
250IU, 500IU, 1000IU
Description
Antihemophilic Facor Human Recombinant produced in CHO is a glycosylated polypeptide chain having 2322 amino acids. The Factor-VIII is purified by proprietary chromatographic techniques.
Storage & Handling
Lyophilized Factor-VIII although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Factor-VIII should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Cite This Product
F8 Coagulation Factor-VIII Human Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP00451)
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Each 250IU vial was lyophilized from a solution containing 8mg Tween-80, 112mM NaCl, 40mg Mannitol, 10mg Trehalose, 1ng VWF and 4.2mM CaCl2.
Purity
Greater than 97.0% as determined by SDS-PAGE.
Predicted MW
267.009kDa
Reconstitution
It is recommended to reconstitute 250IU lyophilized Factor-VIII in 5ml sterile 18M-cm H2O, which can then be further diluted to other aqueous solutions.
Biological Activity
The specific activity was found to be 7,058 IU/mg.
Assay dilution & Images
Reconstitution
It is recommended to reconstitute 250IU lyophilized Factor-VIII in 5ml sterile 18M-cm H2O, which can then be further diluted to other aqueous solutions.
Validation Images & Assay Conditions
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Recombinant protein fun image
Protein Target Info & Infographic
Gene/Protein Information For F8 (Source: Uniprot.org, NCBI)
Gene Name
F8
Full Name
Coagulation factor VIII
Weight
267.009kDa
Superfamily
multicopper oxidase family
Alternative Names
Coagulation factor VIII; Procoagulant component; Antihemophilic factor; AHF; F8; F8C; F8B; HEMA; FVIII; DXS1253E; F8 protein F8 AHF, DXS1253EB, F8C, FVIII, HEMA, F8 coagulation factor VIII coagulation factor VIII|antihemophilic factor|coagulation factor VIII A1 domain|coagulation factor VIII C2 domain|coagulation factor VIII, procoagulant component|coagulation factor VIIIc|factor VIII F8B
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on F8, check out the F8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for F8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For F8 Coagulation Factor-VIII Human Recombinant Protein (PROTP00451)
Hello CJ!
PROTP00451 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Angiotensin-Converting Enzyme Inhibition Attenuates Lipopolysaccharide-Induced Lung Injury by Regulating the Balance Between Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 and Inhibiting Mitogen-Activated Protein Kinase Activation
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Customer Reviews
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Customer Q&As
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4 Customer Q&As for F8 Coagulation Factor-VIII Human Recombinant Protein
Question
What is the recommended expiry date once the lyophilized vial is reconstituted and stored at -20 for PROTP00451? Your website mentions ‘Store in -20C for long term storage’ and what do you define as long term storage? Is there an expiry date for the item which is shipped in powder form (maybe on the CofA)?
Verified customer
Asked: 2020-05-27
Answer
Our proteins are stable for at least 12m from their export date prior to their reconstitution while stored at the mentioned storage conditions. We do not obtain stability data post reconstitution over different periods of time.
Boster Scientific Support
Answered: 2020-05-28
Question
Apart from the 250IU PROTP00451, do you provide other sizes of vials?
Verified customer
Asked: 2020-05-27
Answer
250IU F8 Coagulation Factor-VIII Human Recombinant Protein (PROTP00451) is our smallest pack size.
Boster Scientific Support
Answered: 2020-05-28
Question
How often is there a change in the batch lot number for PROTP00451 and is there a batch to batch variation in the potency/activity measured?
Verified customer
Asked: 2020-05-27
Answer
Every batch of our F8 Coagulation Factor-VIII Human Recombinant Protein (PROTP00451) has a batch number, once we clear the stock we produce a new one.
Boster Scientific Support
Answered: 2020-05-28
Question
We are looking at purchasing recombinant factor VIII to construct the standard curve on a potency assay we are developing and we are hoping that this assay could be used as a QC release method for a commercial product in the future. Could you confirm that the TandC include the use of PROTP00451?
Verified customer
Asked: 2020-05-27
Answer
F8 Coagulation Factor-VIII Human Recombinant Protein (PROTP00451) and all our proteins are for research use only.
Boster Scientific Support
Answered: 2020-05-28
