Zinc finger protein 503 Antibodies

Zinc finger protein 503 (ZNF503)

May function as a transcriptional repressor. .

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Gene Information

Human
Gene Name:	ZNF503
Uniprot:	Q96F45
Entrez:	84858

Family

Belongs to:
Elbow/Noc family

Alternative Names

KOX17Zinc finger protein 191; lacks zinc finger domain; Retinoic acid suppression protein A; RSG-A; Zfp191; Zinc finger and SCAN domain-containing protein 3; zinc finger protein 24 (KOX 17); zinc finger protein 24; ZNF191; ZSCAN3Zinc finger protein KOX17

Molecular Weight

Mass (kDA):
62.555 kDA

Genomic Context

Human
Location:	10q22.2
Sequence:	10; NC_000010.11 (75279726..75401894, complement)

Subcellular Localizations

Nucleus.

Pathways

• Endoderm Formation
• Histone Deacetylation
• Gastrulation
• Developmental Growth

PTMs

• Acetylation

• Methylation

• Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF503

Boster Bio - Best Uses Of The ZNF503 Marker

Boster offers primary antibody against Zinc finger protein 503. This well-studied target has many applications. Their antibodies have been extensively referenced for more than 20 years and are trusted by the research community. They are validated in Western Blotting, Immunohistochemistry, and ELISA. The detection and validation of the ZNF503 marker in human samples have been extensive for the Boster antibodies.

Antibodies for Zinc finger protein 503

Antibodies to detect Zinc finger protein503 have been developed to monitor this gene in many biological assays. They can react to a wide range animal samples and can either be monoclonal (or polyclonal) Boster Bio developed antibodies to ZNF503 in rabbit and mouse. Both Lys N and trypsin both cover complementary portions the phosphoproteome.

These domains can be modified in order to target specific sequences because zinc finger proteins recognize 3 base pairs independently. To make the entire protein more precise, you could change the -1, 3 and 6 positions within one domain. Modifying zinc finger proteins modularly led to the hypothesis of individual domains being interchangeable and conferring new binding specificity to the entire protein. This may allow the identification unique sequences.

Alterations in cell cycle and proliferation are closely tied to aberrant expressions. However, the underlying molecular mechanism is not completely understood. Two forms of the zinc finger protein ZER6 are available: p52ZER6 (or p71ZER6). Although their biological function is not fully understood, their role in tumorgenesis remains crucial.

There is evidence that ZFP503 may promote aggressive breast carcinoma. Recent studies have suggested that the zinc finger mutant RPAm is not able to form detectable replication products but has a similar functional profile to wild type RPA. It is not known how it functions in DNA repair. Antibodies to detect Zinc finger protein 503 have not yet been characterized, but future research will clarify whether it promotes or inhibits breast cancer development.

Interactions with PSEN1, DLGAP5 and SPEF1

Boster's gene infographics provide basic information about each gene. The human and mouse versions have gene expression in 154 different tissues. These include the Esophagus' squamous epithelium, and the jejunal moucosa. The search bar can be used to locate the gene of your interest. This site contains over 2,000 gene annotations which makes it an excellent resource.

Applications

The ZNF503 transcriptional repressor has been implicated as a factor in the development and progression of many types of cancer. Unconjugated antibodies can be used to achieve its synthesis. This marker can be used for Western Blot analysis and ELISA. The ZNF503 marker, despite its unconjugated antibody composition, is stable at 4°C and can be used for a variety applications.

History of Steven Boster

He is best known for his creation of the revolutionary antigen/antibody ELISA. His history with Steven Boster dates back to 1993 when he created his first product. His work earned him the nickname "he who converts science into lavatory science." He has since developed hundreds of primary antibodies, and he is now one of the most important catalog antibody companies in China. Later, in the 1990s, he developed a proprietary ELISA platform known as PicoKine(tm). He produces high-sensitivity ELISA tests that are highly useful for research.

Steve Boster's death occurred on June 26, 2022. He was a retired manager of retail sales. He was also a member Concordia Hall, Staunton. He is survived by his wife of 42 year, Natosha, and Crystal Boster, as well as six grandchildren and four brothers. His sister Kimberly is a former Martha Stewart model. Many nieces, nephews, and nephews survived Steve.