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- Table of Contents
Facts about Zinc finger protein 335.
Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain growth, including REST. Also controls the expression of genes involved in somatic growth and regulates, for example, lymphoblast proliferation.
Human | |
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Gene Name: | ZNF335 |
Uniprot: | Q9H4Z2 |
Entrez: | 63925 |
Belongs to: |
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krueppel C2H2-type zinc-finger protein family |
DKFZp586G1122; Hzf; HZFzinc finger protein 385; RZFHematopoietic zinc finger protein; ZFP385; zinc finger protein 385A; ZNF385Retinal zinc finger protein
Mass (kDA):
144.893 kDA
Human | |
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Location: | 20q13.12 |
Sequence: | 20; NC_000020.11 (45948653..45972910, complement) |
Ubiquitously expressed.
Nucleus.
PMID: 12215545 by Mahajan M.A., et al. NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC.
PMID: 18180299 by Garapaty S., et al. Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1.