YEATS domain-containing protein 2 (YEATS2)

Chromatin reader part of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at'Lys-27' (H3K27cr) (PubMed:27103431).

Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431). .