Xylosyltransferase 2 Antibodies

AND XYLT2 ELISA kits, Xylosyltransferase 2 Proteins

Many biological assays use antibodies to detect Xylosyltransferase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Xylosyltransferase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Xylosyltransferase 2 antibodies...

We validate the specificity of these antibodies to Xylosyltransferase 2 by testing them on tissues known to express XYLT2 positively and negatively. Browse below to find the XYLT2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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XYLT2 Infographic by Boster Bio

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XYLT2 (NM_022167) Human Over-expression Lysate

Human

$628
Cat # LS064132
100 µg

XYLT2 Overview

Facts about Xylosyltransferase 2.

XYLT2 3D structure. Source: alphafold

Xylosyltransferase 2 (XYLT2)

Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.

Gene Information

Human
Gene Name:	XYLT2
Uniprot:	Q9H1B5
Entrez:	64132

Family

Belongs to:

glycosyltransferase 14 family

Alternative Names

Xylosyltransferase 2

Molecular Weight

Mass (kDA):
96.767 kDA

Genomic Context


Human

Location:	17q21.33
Sequence:	17; NC_000017.11 (50346126..50361185)

Tissue Specificity

Widely expressed. Expressed at higher level in kidney and pancreas.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/XYLT2

References

PMID: 11099377 by Goetting C., et al. Molecular cloning and expression of human UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase and its first isoform XT-II.

PMID: 16571645 by Schon S., et al. Polymorphisms in the xylosyltransferase genes cause higher serum XT-I activity in patients with pseudoxanthoma elasticum (PXE) and are involved in a severe disease course.