Serine/threonine-protein kinase WNK3 (WNK3)

Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011).

Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2.