This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Serine/threonine-protein kinase WNK3.
Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2.
Human | |
---|---|
Gene Name: | WNK3 |
Uniprot: | Q9BYP7 |
Entrez: | 65267 |
Belongs to: |
---|
protein kinase superfamily |
EC 2.7.11; FLJ30437; KIAA1566FLJ42662; PRKWNK3lysine deficient 3; WNK lysine deficient protein kinase 3
Mass (kDA):
198.416 kDA
Human | |
---|---|
Location: | Xp11.22 |
Sequence: | X; NC_000023.11 (54192823..54358695, complement) |
Expressed in brain, lung, kidney, liver and pancreas, and in fetal tissues including placenta, fetal brain, lung and kidney. Very low levels of expression were also detected in fetal heart, thymus, liver and spleen. Isoform 1 is brain- specific. Isoform 3 is kidney-specific.
Cytoplasm.
PMID: 11571656 by Verissimo F., et al. WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.
PMID: 15194194 by Holden S., et al. Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3).