VPS16 Antibodies

AND VPS16 ELISA kits, VPS16 Proteins

Many biological assays use antibodies to detect VPS16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VPS16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VPS16 antibodies...

We validate the specificity of these antibodies to VPS16 by testing them on tissues known to express VPS16 positively and negatively. Browse below to find the VPS16 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VPS16 Infographic by Boster Bio

All VPS16 Products

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Product

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Specificity

Applications

Price

Anti-VPS16 Antibody

Human, Mouse, Rat

$405
Cat # A06384
100ul

VPS16 (NM_080413) Human Over-expression Lysate

Human

$960
Cat # LS064601
100 µg

VPS16 Overview

Facts about Vacuolar protein sorting-associated protein 16 homolog.

VPS16 3D structure. Source: alphafold

Vacuolar protein sorting-associated protein 16 homolog (VPS16)

Plays a role in vesicle-mediated protein trafficking into lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to function as a core part of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion likely implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.

The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion likely in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for recruiting of VPS33A into the HOPS complex (PubMed:23901104).

Gene Information

Human
Gene Name:	VPS16
Uniprot:	Q9H269
Entrez:	64601

Family

Belongs to:

VPS16 family

Alternative Names

hVPS16; vacuolar protein sorting 16 homolog (S. cerevisiae); vacuolar protein sorting protein 16; vacuolar protein sorting-associated protein 16 homolog

Molecular Weight

Mass (kDA):
94.694 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (2840697..2866732)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic vesicle, autophagosome. Colocalizes with AP-3, clathrin, Rab5 and Rab7b (By similarity). Cytoplasmic, peripheral membrane protein associated with early endosomes and late endosomes/lysosomes.