UACA Antibodies

AND UACA ELISA kits, UACA Proteins

Many biological assays use antibodies to detect UACA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UACA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UACA antibodies...

We validate the specificity of these antibodies to UACA by testing them on tissues known to express UACA positively and negatively. Browse below to find the UACA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UACA Infographic by Boster Bio

All UACA Products

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Product

Figures

Specificity

Applications

Price

Anti-UACA / Nucling (Nuclear Membrane Marker) Monoclonal Antibody

6 Q&As

Human, Mouse

$486
Cat # M07252
100ug/vial

Anti-UACA Antibody

Human, Mouse, Rat

$405
Cat # A07252
100ul

UACA Overview

Facts about Uveal autoantigen with coiled-coil domains and ankyrin repeats.

UACA 3D structure. Source: alphafold

Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA)

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation.

Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

Gene Information

Human
Gene Name:	UACA
Uniprot:	Q9BZF9
Entrez:	55075

Family

Belongs to:

No superfamily

Alternative Names

FLJ10128; KIAA1561MGC141969; MGC141967; nuclear membrane binding protein; NUCLING; uveal autoantigen with coiled coil domains and ankyrin repeats; uveal autoantigen with coiled-coil domains and ankyrin repeats

Molecular Weight

Mass (kDA):
162.505 kDA

Genomic Context


Human

Location:	15q23
Sequence:	15; NC_000015.10 (70654554..70778823, complement)

Tissue Specificity

Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells.