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- Table of Contents
Facts about Tapasin-related protein.
Expression seems to slow down and down-regulate MHC class I surface expression. .
Human | |
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Gene Name: | TAPBPL |
Uniprot: | Q9BX59 |
Entrez: | 55080 |
Belongs to: |
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No superfamily |
FLJ10143; TAP binding protein-like; Tapasin Related Protein/TAPBPR; Tapasin-like; TAPASIN-R; tapasin-related protein; TAP-binding protein-like; TAP-binding protein-related protein; TAPBPL; TAPBPR; TAPBP-RTAP binding protein related; TAPBPRtapasin-like
Mass (kDA):
50.183 kDA
Human | |
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Location: | 12p13.31 |
Sequence: | 12; NC_000012.12 (6451656..6472006) |
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Microsome membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Mainly found in endoplasmic reticulum but a minority is found on the cell surface (PubMed:11920573).
PMID: 11920573 by Teng M.S., et al. A human TAPBP (TAPASIN)-related gene, TAPBP-R.
PMID: 23401559 by Boyle L.H., et al. Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway.