STYK1 Antibodies

AND STYK1 ELISA kits, STYK1 Proteins

Many biological assays use antibodies to detect STYK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STYK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STYK1 antibodies...

We validate the specificity of these antibodies to STYK1 by testing them on tissues known to express STYK1 positively and negatively. Browse below to find the STYK1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STYK1 Infographic by Boster Bio

All STYK1 Products

Product

Figures

Specificity

Applications

Price

Anti-NOK STYK1 Monoclonal Antibody

Human

ELISA, IHC, WB

$380
Cat # M07376
100ul

STYK1 (NM_018423) Human Recombinant Protein

$1249
Cat # PROTQ6J9G0
20 µg

STYK1 (NM_018423) Human Over-expression Lysate

Human

$628
Cat # LS055359
100 µg

STYK1 Overview

Facts about Tyrosine-protein kinase STYK1.

STYK1 3D structure. Source: alphafold

Tyrosine-protein kinase STYK1 (STYK1)

Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in remote organs.

May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity). .

Gene Information

Human
Gene Name:	STYK1
Uniprot:	Q6J9G0
Entrez:	55359

Family

Belongs to:

protein kinase superfamily

Alternative Names

DKFZp761P1010; EC 2.7.10.2; NOK; NOKProtein PK-unique; serine/threonine/tyrosine kinase 1Novel oncogene with kinase domain; STYK1; SuRTK106; tyrosine-protein kinase STYK1

Molecular Weight

Mass (kDA):
47.577 kDA

Genomic Context


Human

Location:	12p13.2
Sequence:	12; NC_000012.12 (10618923..10674318, complement)

Tissue Specificity

Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers.

Subcellular Localizations

Membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Mammary Neoplasms
Neoplasm Metastasis
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Metaplastic Cell Transformation
Malignant Neoplasm Of Prostate
Lung Neoplasms
Non-small Cell Lung Carcinoma
Malignant Paraganglionic Neoplasm
Neoplasm Invasiveness

Malignant Neoplasm Of Lung
Acute Leukemia
Prostatic Neoplasms
Acute Promyelocytic Leukemia
Leukemia
Malignant Neoplasm Of Ovary

Interacting Proteins

GSK3B

Pathways

Cell Proliferation
Reverse Transcription
Cell Migration
Cell Growth

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STYK1

References

PMID: 12841579 by Ye X., et al. Isolation and characterization of a human putative receptor protein kinase cDNA STYK1.

PMID: 15150103 by Liu L., et al. A novel protein tyrosine kinase NOK that shares homology with platelet-derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice.