PI4K2A Antibodies

AND PI4K2A ELISA kits, PI4K2A Proteins

Many biological assays use antibodies to detect PI4K2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PI4K2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PI4K2A antibodies...

We validate the specificity of these antibodies to PI4K2A by testing them on tissues known to express PI4K2A positively and negatively. Browse below to find the PI4K2A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PI4K2A Infographic by Boster Bio

All PI4K2A Products

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Specificity

Applications

Price

Anti-P4K2A PI4K2A Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06809
100ul

PI4K2A (NM_018425) Human Recombinant Protein

$1062
Cat # PROTQ9BTU6
20 µg

PI4K2A (NM_018425) Human Over-expression Lysate

Human

$628
Cat # LS055361
100 µg

PI4K2A Overview

Facts about Phosphatidylinositol 4-kinase type 2-alpha.

PI4K2A 3D structure. Source: alphafold

Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A)

Membrane-bound phosphatidylinositol-4 kinase (PI4- kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) into phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is needed for prolonged survival of neurons. Besides, phosphorylation of phosphatidylinositol (PI) into phosphatidylinositol 4-phosphate (PI4P) is the first committed step in the creation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).

Gene Information

Human
Gene Name:	PI4K2A
Uniprot:	Q9BTU6
Entrez:	55361

Family

Belongs to:

PI3/PI4-kinase family

Alternative Names

DKFZp761G1923; EC 2.7.1.67; phosphatidylinositol 4-kinase type 2 alpha; phosphatidylinositol 4-kinase type 2-alpha; phosphatidylinositol 4-kinase type II (PI4KII); Phosphatidylinositol 4-kinase type II-alpha; PI4KII; PIK42A; RP11-548K23.6

Molecular Weight

Mass (kDA):
54.022 kDA

Genomic Context


Human

Location:	10q24.2
Sequence:	10; NC_000010.11 (97640686..97676434)

Tissue Specificity

Widely expressed. Highest expression is observed in kidney, brain, heart, skeletal muscle, and placenta and lowest expression is observed in colon, thymus, and small intestine.

Subcellular Localizations

Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Membrane raft. Cell projection, dendrite. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, synaptosome. Mitochondrion. Endosome. Cytoplasmic vesicle. Membrane; Lipid-anchor. Cell membrane. Perikaryon. Cell projection, neuron projection. Found in subdomains of the plasma membrane termed non-caveolar membrane rafts. Transported from neuronal cell body to neuron projections and neurite tips in a BLOC-1- and AP-3-complexes-dependent manner.