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- Table of Contents
Facts about Spectrin beta chain, non-erythrocytic 4.
Human | |
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Gene Name: | SPTBN4 |
Uniprot: | Q9H254 |
Entrez: | 57731 |
Belongs to: |
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spectrin family |
beta-IV spectrin; KIAA1642; QV; spectrin beta chain, brain 3; spectrin, beta, non-erythrocytic 4; spectrin, non-erythroid beta chain 3; SPNB4; SPTBN3
Mass (kDA):
288.985 kDA
Human | |
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Location: | 19q13.2 |
Sequence: | 19; NC_000019.10 (40467001..40576464) |
Expressed in skeletal muscle at the sarcolemma and in the muscle capillaries (at protein level) (PubMed:28540413). Abundantly expressed in brain and pancreatic islets (PubMed:11086001).
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
PMID: 11294830 by Tse W.T., et al. A new spectrin, beta-IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.
PMID: 11086001 by Berghs S., et al. BetaIV spectrin, a new spectrin localized at axon initial segments and nodes of Ranvier in the central and peripheral nervous system.