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- Table of Contents
Facts about Cytosolic beta-glucosidase.
Possesses beta- glycosylceramidase action and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. .
Human | |
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Gene Name: | GBA3 |
Uniprot: | Q9H227 |
Entrez: | 57733 |
Belongs to: |
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glycosyl hydrolase 1 family |
CBG; CBGL1; CBGL1GLUC; Cytosolic betaGlucosidase; Cytosolic beta-Glucosidase; Cytosolic beta-glucosidase-like protein 1; EC 3.2.1.21; GBA3; GLUC; glucosidase, beta, acid 3 (cytosolic); klotho-related protein; KLrP; MGC104276; MGC126878
Mass (kDA):
53.696 kDA
Human | |
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Location: | 4p15.2 |
Sequence: | 4; NC_000004.12 (22692937..22819569) |
Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
Cytoplasm, cytosol.
PMID: 11043382 by Yahata K., et al. Molecular cloning and expression of a novel klotho-related protein.
PMID: 11389701 by de Graaf M., et al. Cloning and characterization of human liver cytosolic beta- glycosidase.